Not to be taken by pregnant or lactating women.
Some ingredients may cause gastrointestinal upset.
In rare cases, alpha lipoic acid may cause skin rash in sensitive individuals.
Rare side effects of N-acetyl-L-cysteine and milk thistle include headache, dry mouth, itching and dizziness.
Milk thistle should be avoided by individuals with allergies to members of the aster (Compositea/Asteraceae) family, daisies, artichoke, kiwi or thistle.
Some studies have reported that milk thistle, calcium-D-glucarate and broccoli sprout extract can affect the way that the liver breaks down medications metabolized by the cytochrome P450 system, altering the effects of these medications and possibly the dose needed for treatment.
Broccoli sprout extract may react with blood thinning medications.
Consult your physician for more information.